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Group 1 Beta-Expansin (Uro m 1) (Uro m 1)
- Target
- Uro m 1
- Molecular classification
- Expansin superfamily, Beta-expansin (EXPB) family, Plant cell wall loosening protein
01
Overview
Group 1 beta-expansin, Uro m 1, is a major allergenic protein found in Para grass (*Urochloa mutica*) pollen. It belongs to the expansin superfamily and functions in plant cell wall loosening, particularly during pollen tube growth. Uro m 1 is a significant allergen for individuals with allergic rhinitis and exhibits strong cross-reactivity with other grass pollen allergens. Multiple isoforms exist, with varying degrees of IgE reactivity.
- Other names
- Beta-expansinPara grass pollen allergenUrochloa mutica group 1 allergenEXPB1
02
Mechanism of action
N/A
03
Biological functions
Cell wall looseningPollen tube growthExtracellular matrix modification
04
Disease associations
Allergic rhinitisPollen allergyAirway allergic rhinitis
05
Safety considerations
AllergenicityCross-reactivity with other grass pollen allergens
06
Biomarkers
IgE reactivity to Uro m 1 isoforms
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