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Guanine nucleotide binding protein, alpha transducing 3 pseudogene

Molecular classification
Other (Pseudogene)
01

Overview

ENSG00000257289, known as guanine nucleotide binding protein, alpha transducing 3 pseudogene, is a processed pseudogene located on chromosome 12[5]. Unlike protein-coding genes, pseudogenes do not result in functional proteins due to mutations or loss of coding potential[1][3][9]. This locus, derived from the GNAT3 gene, shows sequence similarity to the functional guanine nucleotide-binding protein subunit alpha transducing 3, but is inactive[1][3]. Pseudogenes may sometimes be transcribed and influence the expression of other genes through regulatory mechanisms such as acting as miRNA “decoys,” but there is no evidence of direct biological or disease-related function or druggability for this specific pseudogene[7][9]. This profile indicates that ENSG00000257289 is not appropriate as a therapeutic target and does not have the biological or pharmacological relevance required for targeted drug discovery or development.

Other names
RP11-611O2.6GNAT3 pseudogene
02

Biological functions

Other (No direct protein-coding function; may have regulatory roles typical of some pseudogenes but not directly established for this locus)
03

Disease associations

Other (no known direct involvement in disease; pseudogenes in general can play regulatory roles in certain contexts, but no disease relevance found for this specific pseudogene)

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