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In humans, Guanylate cyclase 2E, pseudogene (GUCY2EP) is an inactivated gene that does not encode a functional enzyme. It is part of the guanylyl cyclase family, originally involved in chemosensation in the mammalian olfactory system, but has been rendered nonfunctional by mutations in humans and most primates. Gene symbols and aliases include GC-E and GUCY2E. In rodents, however, the functional homolog participates in olfactory signal transduction as a membrane-bound guanylyl cyclase[1][2][7].
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