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Target intelligence / Profile preview
H2A clustered histone 10, pseudogene (H2AC10P)
- Target
- H2AC10P
- Molecular classification
- Histone pseudogene, Core histone family (H2A type)
01
Overview
H2A clustered histone 10, pseudogene (H2AC10P) is a member of the human histone gene family classified as a pseudogene[4]. While canonical histone H2A proteins participate in the core nucleosome structure and DNA organization within chromatin, H2AC10P does not encode a functional histone protein due to its disrupted coding sequence and lack of necessary regulatory elements[2][3][4]. It represents a non-functional genomic locus, and there is no evidence that it is involved in disease processes or therapeutic drug targeting. The presence of such pseudogenes is common among histone gene clusters and reflects the evolutionary remnants of replication-dependent histone gene structures[4].
- Other names
- HIST1H2APS4H2AFKH2AFKPH2A/kpH2A/kdJ34B20.2histone cluster 1 H2A pseudogene 4H2a histone family, member K, pseudogenehistone 1 H2a pseudogene 4
02
Mechanism of action
none (no protein product, so no pharmacological mechanism)
03
Biological functions
No direct biological function, as it is a pseudogeneFunctional H2A proteins are involved in DNA packaging, nucleosome formation, and gene regulation, but H2AC10P does not produce a protein.
04
Disease associations
None established; pseudogenes generally lack direct pathogenic rolesNo documented association with disease as an active contributor
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