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Target intelligence / Profile preview
H2B clustered histone 20, pseudogene (H2BC20P)
- Target
- H2BC20P
- Molecular classification
- Histone, Pseudogene, Structural constituent of chromatin
01
Overview
H2B clustered histone 20, pseudogene (H2BC20P) is a histone H2B family pseudogene found in a histone gene cluster on chromosome 1[1][5][7]. While functional histone H2B proteins are integral components of nucleosomes, essential for DNA compaction, chromatin structure, and regulation of gene expression, H2BC20P itself is classified as a pseudogene and is not believed to produce a functional protein product[1][7]. Pseudogenes such as H2BC20P do not typically serve as therapeutic targets, and there is no evidence of direct disease involvement, drug interactions, or utility as a biomarker[1][2][5].
- Other names
- HIST2H2BCH2B/tLETNHistone H2B.tlncRNA essential for tumor cell proliferation via NPM1HIST2H2BDH2B/shistone cluster 2 H2B family member c (pseudogene)histone cluster 2, H2bc (pseudogene)
02
Biological functions
Chromatin structureDNA packaging(Predicted) DNA binding(Predicted) Protein heterodimerization
03
Disease associations
Other
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