H3 clustered histone 9, pseudogene (H3C9P)

H3 clustered histone 9, pseudogene (**H3C9P**; also known as HIST1H3PS1, among other aliases) is annotated as a **pseudogene** within the histone H3 gene cluster on chromosome 6p22.2[2]. Unlike canonical histone H3 proteins, this locus does not encode a functional protein and is not transcribed or translated under normal physiological conditions. While protein-coding histone H3 genes play central roles in DNA packaging into nucleosomes and regulation of chromatin structure[4][5], pseudogenes like H3C9P do not contribute to these cellular processes and are generally considered non-functional remnants of histone gene duplications. There is no evidence in the biomedical literature for H3C9P being a receptor, enzyme, therapeutic target, or biomarker, and it is not implicated in any known disease mechanisms, drug interactions, or therapeutic safety concerns[2][4].\n\n**Key points:**\n- H3C9P is a pseudogene, not a protein-coding gene.\n- It does not represent a therapeutic target.\n- The presence of multiple aliases reflects alternative database or historical gene naming but does not indicate functional diversity[2].\n- There is no established relevance to pathophysiology, therapeutics, or diagnostics.\n\n**Note on correctness:** \nThe query lists H3C9P as a target molecule/receptor, but in standard gene/protein nomenclature H3C9P is a *non-functional pseudogene* associated with the histone H3 family, not a protein, receptor, or druggable target[2][4].

Other names

dJ45P21.6H3F3AP1p36HIST1H3PS1histone cluster 1 H3 pseudogene 1histone 1, H3, pseudogene 1