Heat shock protein 90kDa alpha, class A member 1 pseudogene

Heat shock protein 90kDa alpha, class A member 1 pseudogene is a non-protein-coding gene that is a pseudogene related to the functional HSP90AA1 gene, which encodes the chaperone protein Hsp90-alpha. Multiple pseudogenes exist for HSP90AA1 throughout the human genome, but they do not code for an active protein, have no known direct function, and are not therapeutic targets. The functional protein-coding gene is HSP90AA1, involved in protein folding and cellular stress response, and is an important cancer drug target. The entity in question is a pseudogene—it does not encode a functional protein. Pseudogenes may occasionally regulate the parent gene through transcript-based mechanisms, but such roles for the HSP90AA1 pseudogenes have not been established in literature, and they are not considered targets. If you are interested in the actual protein target (Hsp90-alpha), its druggability, or disease roles, you should reference "heat shock protein 90kDa alpha, class A member 1" (HSP90AA1), not the pseudogene.

Other names

HSP90AA1 pseudogeneHeat shock protein 90-alpha pseudogene

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