Heat shock protein 90kDa alpha, class B member 1 pseudogene

"Heat shock protein 90kDa alpha, class B member 1 pseudogene" refers to a non-functional genomic DNA segment that resembles the protein-coding gene HSP90AB1 but cannot encode a functional protein. Pseudogenes, unlike their protein-coding counterparts, typically lack regulatory elements or contain mutations (e.g., premature stop codons, frameshifts) that prevent their translation into an active protein. Therefore, this pseudogene is not implicated in molecular chaperone activities or therapeutic targeting; all clinical and functional data associated with 'heat shock protein 90kDa alpha, class B member 1' refer to the protein product of the HSP90AB1 gene, not the pseudogene[5][3]. Key clarification: - The *functional protein-coding target* relevant for heat shock protein 90kDa alpha, class B member 1 (HSP90AB1, HSP90β) is a widely studied molecular chaperone involved in cell cycle regulation, protein folding, and is a well-validated oncology target. The pseudogene (such as ENSG00000237016) does not share these properties, should not be annotated as a receptor, enzyme, or molecular target, and is not relevant for pharmacological intervention[1][5]. - *If you intended the protein-coding HSP90AB1 (not pseudogene), please clarify, as that would yield a very different, target-rich-specific profile.

Other names

Heat shock protein 90kDa alpha (cytosolic), class B member 1 pseudogeneheat shock protein 90kDa alpha family class B member 1 pseudogeneLOC100129456