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A surface antigen is a molecule, typically a protein or glycoprotein, found on the outer surface of bacteria or viruses. These antigens serve as markers that are recognized by the host immune system, triggering an immune response. Surface antigens are critical for pathogen identification and are often targets for diagnostic tests and vaccine development. They can induce antibody production and are involved in various processes like cell adhesion, receptor binding, and immune evasion. Examples include HBsAg in HBV and pneumococcal polysaccharide/protein antigens.
Induction of antibody production and T-cell activation leading to adaptive immunity.
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