House dust mite allergen Der p 2 (or Der f 2, depending on species) (Der p 2 (for Dermatophagoides pteronyssinus), Der f 2 (for Dermatophagoides farinae))

House dust mite organism" is not a specific molecular target but refers to the entire organism. The relevant therapeutic targets are the **major allergens** produced by house dust mites, particularly proteins such as **Der p 2** and **Der f 2**, which are responsible for triggering allergic reactions in humans. These allergens have a beta-barrel structure similar to immunoglobulin folds and induce strong Th2-type immune responses that can lead to asthma, rhinitis, and eczema in susceptible individuals[1][3]. The high sequence and structural similarity between group 2 allergens from different species suggests similar biological functions across mites[4]. These proteins are not receptors or enzymes but act as environmental antigens/allergens. Note: "House dust mite organism" is too broad for a molecular target entry; the correct entries should be individual allergens such as "House dust mite allergen Der p 2".

Other names

Major house dust mite allergenGroup 2 house dust mite allergenDer p 2 (Dermatophagoides pteronyssinus)Der f 2 (Dermatophagoides farinae)