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Target intelligence / Profile preview
Human Immunodeficiency Virus Type 1 Antigen (Gag p24) (None)
- Target
- None
- Molecular classification
- Viral protein, Structural protein
01
Overview
The HIV-1 Gag p24 protein is a major structural component of the human immunodeficiency virus type 1 (HIV-1) capsid, forming the core shell that encases and protects the viral RNA genome. It is essential for viral replication, assembly, and infectivity. Detection in blood serves as an early indicator for acute HIV infection and is a biomarker for monitoring disease progression or treatment efficacy. Recombinant forms are used as standards in ELISA/Western blot assays. It has been also explored as a vaccine antigen candidate.
02
Mechanism of action
N/A
03
Biological functions
Viral capsid formationViral replicationViral assemblyViral infectivityGenome packaging
04
Disease associations
InfectionHIV/AIDS
05
Interacting drugs
Antiretroviral therapies (indirectly, by inhibiting HIV protease)
06
Biomarkers
Early indicator of acute HIV infectionBiomarker for monitoring disease progressionBiomarker for monitoring treatment efficacy
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