Immediate early protein 2 (HCMV) (IE2)

IE2-exon5 refers to the fifth exon within the human cytomegalovirus UL122 gene, which encodes part of the immediate early protein 2 (IE2) family, including isoforms such as IE2-86, IE2-60, and IE2-40[2][9]. This region is necessary for the production of key viral transcription factors that regulate the initiation of viral and selected host gene transcription during acute infection[2][7]. Proteins containing this exon are essential for efficient viral replication, particularly in the late phase, and play key roles in both activation and repression of viral gene expression[7][2]. However, "IE2-exon5" is not a standard molecular target term; its use is primarily for research on the function of specific domains in viral gene expression and immune recognition[1].

Other names

UL122 exon 5IE2 exon 5IE2-86IE2-60IE2-40

Not applicable; the region is not a recognized drug target distinct from the parent protein.