Immune System (Desensitization via Allergen Exposure)

Desensitization of the immune system through allergen exposure, also known as allergen immunotherapy, is a medical approach used to reduce or eliminate allergic reactions by gradually training the immune system to tolerate specific allergens. This process involves controlled and repeated exposure to increasing doses of an allergen, either via injections or sublingual administration. The therapy aims to induce tolerance by modulating immune cell populations and antibody production, leading to long-term relief from allergy symptoms.

Other names

Allergen ImmunotherapyDesensitizationAllergy ShotsSublingual Immunotherapy (SLIT)Subcutaneous Immunotherapy (SCIT)

Gradual exposure to allergen induces regulatory T cells, shifts antibody production from IgE to IgG4/IgA, and reduces mast cell and basophil activation.