Immune system (induction of immune tolerance to Fel d 1)

The induction of immune tolerance to Fel d 1, the major cat allergen, involves modulating the immune response so that exposure no longer triggers an allergic reaction. Immunotherapeutic strategies include allergen immunotherapy (AIT) with adjuvants, peptide immunotherapy targeting T-cell epitopes, and novel delivery systems such as fusion proteins and virus-like particles. These approaches aim to re-educate the immune system, promoting regulatory T cell expansion and shifting the balance away from Th2-mediated allergic responses.

Other names

Fel d 1 immunotherapyCat allergy tolerance induction

Modulating the immune response to Fel d 1 to induce tolerance and prevent allergic reactions. Strategies include promoting Treg cell expansion, shifting cytokine profiles, and engaging inhibitory receptors.