Immune System (Induction of Specific Immune Tolerance)

The induction of specific immune tolerance refers to the process by which the immune system is rendered unresponsive or less responsive to a particular antigen, while maintaining its ability to respond to other antigens. This mechanism is crucial for preventing autoimmune diseases, enabling successful organ transplantation, and reducing allergic responses. Strategies involve manipulating dendritic cells, promoting regulatory T cell development, and delivering antigens in a tolerogenic manner.

Other names

Specific Immune ToleranceTolerance InductionAntigen-Specific Tolerance

Induction of central and peripheral tolerance mechanisms, including clonal deletion, anergy, suppression by regulatory T cells (Tregs), and anti-inflammatory cytokines.