Immune system (T-cell mediated desensitization)

T-cell mediated desensitization refers to the process by which the immune system, particularly T cells, is modulated to reduce or eliminate hypersensitivity reactions to specific antigens (such as allergens or drugs). This process is central in allergen immunotherapy and drug desensitization protocols, aiming to induce tolerance and prevent adverse immune responses. It involves induction/expansion of regulatory T cell populations, suppression/anergy/deletion of effector T cell populations, and increased production of anti-inflammatory cytokines such as IL-10 and IL-35.

Induction/expansion of regulatory T cells, suppression/anergy/deletion of effector T cells, increased production of anti-inflammatory cytokines (IL-10, IL-35)