Immunoglobulin heavy variable (III)-67-3 (pseudogene) (IGHVIII-67-3)

This gene segment encodes a pseudogene of the immunoglobulin heavy variable region, subclass III, variant 67-3. Immunoglobulin heavy variable pseudogenes do not produce functional antibody proteins but are remnants in the genome, likely resulting from gene duplication and mutation events. Unlike functional immunoglobulin heavy variable genes, which contribute to antigen binding diversity in the immune system through V(D)J recombination, pseudogenes like IGHVIII-67-3 are transcriptionally silent or result in non-functional transcripts. These pseudogenes are not considered drug targets and have no disease relevance or associated therapeutics[2][3][4][6].

Other names

3-67.3PIGHV(III)-6IGHVIII673IGHV(III)-67-3IGHVIII-67-3