Immunoglobulin kappa variable 1D-35 (pseudogene) (IGKV1D-35)

Immunoglobulin kappa variable 1D-35 (IGKV1D-35) is a human pseudogene mapped to chromosome 2. It belongs to the group of kappa variable genes that contribute to antibody light chain gene diversity; however, this specific segment is not functional and does not produce a protein. As a variable segment pseudogene, it is included in reference gene tables for immunoglobulin genes but is not considered a therapeutic target and does not serve as a biomarker or druggable entity. Functionally, immunoglobulin variable segments are part of the gene cluster that enables antibody diversity through somatic recombination in B cells; however, pseudogenes like IGKV1D-35 have accumulated mutations or deletions and cannot participate in this process.

Other names

IGKV1D35O6

None, as it does not produce a functional protein