Immunoglobulin kappa variable 2D-23 (pseudogene) (IGKV2D-23)

Immunoglobulin kappa variable 2D-23 (IGKV2D-23) is a human immunoglobulin pseudogene within the kappa light chain variable region locus of chromosome 2p11.2. It belongs to a large family of variable region genes responsible for antigen recognition in functional immunoglobulins, but IGKV2D-23 itself does not encode a functional protein and is categorized as a pseudogene. While functional immunoglobulin kappa variable domains contribute to the diversity of antibodies produced by B lymphocytes, IGKV2D-23 lacks a coding capacity and does not participate in immune functions, disease processes, or serve as a drug target. The nomenclature "2D-23" designates its location in the distal (D) segmental duplication region of the IGK locus, which is rich in both functional and pseudogene members.

Other names

Immunoglobulin kappa variable region gene 2D-23IGKV2D-23