Immunoglobulin kappa variable 3D-25 (pseudogene) (IGKV3D-25)

Immunoglobulin kappa variable 3D-25 is classified as a **pseudogene** belonging to the immunoglobulin kappa variable gene family. This gene segment is part of the variable domain genes that encode the light chain of immunoglobulins, which participate in antigen recognition. However, as a **pseudogene**, IGKV3D-25 does not encode a functional protein and is not expressed as part of the antibody structure, nor is it a direct therapeutic target or involved in known disease mechanisms[1][4]. It is not a functional receptor, enzyme, or genuine drug target but is catalogued as part of the immunoglobulin locus, significant mainly in immunogenetic and evolutionary studies. **Key notes:** - This entry does not correspond to a functional molecule or therapeutic target but rather to a genomic pseudogene segment[1][4]. - There are closely related pseudogene members in the same family, such as IGKV3D-31 and IGKV3D-34, and alternative nomenclatures including IGKV3-25 for similar pseudogenes[4]. - Inclusion of "(pseudogene)" is critical for the canonical name, as absence of this would incorrectly refer to a non-pseudogene functional kappa variable gene, which may have very different biological properties.

Other names

IGKV3D25A6