Immunoglobulin lambda variable (I)-42 (pseudogene) (IGLVI-42)

Immunoglobulin lambda variable (I)-42 (IGLVI-42) is a **human pseudogene** located within the lambda light chain variable region locus of immunoglobulin genes[2][3][5]. Immunoglobulin variable region genes are critical for generating antibody diversity; however, pseudogenes like IGLVI-42 contain genetic alterations (such as frameshift mutations or premature stop codons) that render them nonfunctional, meaning they do not encode a protein product and do not contribute directly to immunity or pathology[3][4]. There is no evidence for expression, functional involvement, disease association, or therapeutic targeting for IGLVI-42. Its identification is used primarily in genomics and immunogenetics to annotate the full repertoire of immunoglobulin gene segments.\n\n*Note: If you are searching for an active immunoglobulin lambda variable region involved in disease, immunity, or serving as a drug target, you should specify a functional member of the IGLV gene family, not a pseudogene.*

Other names

IGLV(I)-42IGLV(I)-42 (pseudogene)IGLVI42V1-15PIGLVI-42