Target intelligence / Profile preview

Immunoglobulin lambda variable (I)-70 pseudogene (IGLVI-70)

Target
IGLVI-70
Molecular classification
Pseudogene, Immunoglobulin lambda variable gene family
01

Overview

Immunoglobulin lambda variable (I)-70 (IGLVI-70) is a pseudogene located within the human immunoglobulin lambda light chain variable (IGLV) locus[5][6]. This locus contributes to the diversity of antibody light chains through recombination of functional variable, joining, and constant segments, but pseudogenes such as IGLVI-70 do not encode a functional immunoglobulin protein and are not expressed in a way that would provide a biological or therapeutic function[5][6]. The presence of such pseudogenes is common in immunoglobulin loci and reflects the complex evolutionary history of these gene families. Summary: IGLVI-70 is not a functional receptor, enzyme, or druggable target but a pseudogene within the immunoglobulin lambda variable gene family. Assigning it as a drug target or biological target would be incorrect based on its current scientific annotation[5][6].

Other names
IGLV(I)-70IGLV(I)-70 pseudogeneIGLVI70V1-27PIG c809_light_IGLV1-36_IGLJ3IGL c3229_light_IGLV1-44_IGLJ3IGLVI-70
02

Biological functions

None (pseudogene, does not encode a functional product)
03

Disease associations

None directly attributable as a biomarker or disease player (does not encode an active peptide)
04

Safety considerations

None (does not encode a functional, targetable protein)
05

Biomarkers

None (not used in clinical biomarker settings)

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