Immunoglobulin lambda variable (VI)-25-1 (IGLVVI-25-1)

Immunoglobulin lambda variable (VI)-25-1 is designated as a pseudogene, meaning it resembles a functional immunoglobulin variable region gene but does not encode a functional immunoglobulin protein product[6][8]. The canonical full name and database entries reflect its similarity to immunoglobulin lambda variable region subgroup VI but with the “25-1” designation[6]. Functional immunoglobulin lambda variable region genes participate in antigen recognition as part of the antibody structure, but this pseudogene is not functionally expressed. As such, it is not considered a therapeutic target, receptor, or biomarker, and has no established disease association or safety profile. The presence of “variable” and “VI” in the name indicates its location and classification within immunoglobulin gene families, but its pseudogene status disqualifies it from biological or pharmacological relevance[6][8]. If you require information on therapeutic targets within the immunoglobulin lambda variable family, such as IGLV3-25 or other functional alleles, those are properly characterized as contributors to antigen binding and immune response[3][4][5], but IGLVVI-25-1 is not one of those due to its pseudogene nature.

Other names

IGLV(VI)-25-1lambdavg3