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Intercellular communication via transfer of microRNAs, proteins, and metabolites" refers to the collective set of biological processes through which cells release and receive diverse small molecules—including microRNAs (miRNAs), proteins, and metabolites—either through membrane-bound vesicles (such as exosomes, microvesicles, and apoptotic bodies), gap junctions, or carrier complexes. These processes play critical roles in regulating gene expression, modulating immune responses, coordinating development and differentiation, and propagating signals in health and immune responses as well as during disease states such as cancer and inflammation. This is not a single defined molecular entity and therefore is not considered a canonical drug target, but rather a foundational mechanism present in many physiological and pathological processes.
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