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JPX transcript, XIST activator conserved region 1 (JPX)

Target: JPX
Molecular classification: Other, lncRNA, non-coding RNA

Overview

JPX transcript, XIST activator conserved region 1 (**JPX**) is a long non-coding RNA gene located on the X chromosome. JPX acts as an RNA activator for XIST, facilitating X chromosome inactivation by upregulating XIST expression. This process is essential for dosage compensation in females, ensuring that one of the two X chromosomes is silenced in each cell[5][11]. JPX does not encode a protein and is not considered a classical therapeutic target, but it plays a critical regulatory role in epigenetics and chromosome biology.

Other names: JPXJPX RNAXIST activatorJPX lncRNA

Biological functions

X chromosome inactivationRegulation of gene expression

Disease associations

Other

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