Target intelligence / Profile preview

Keratin, type I cytoskeletal 39 (KRT39)

Target: KRT39
Molecular classification: Intermediate filament protein, Type I (acidic) keratin, Cytoskeletal protein

Overview

Keratin, type I cytoskeletal 39 (KRT39) is a member of the type I (acidic) keratin family of intermediate filament proteins, primarily expressed in the skin and hair follicle, especially in the upper hair cuticle and cortex. It functions as a structural component, contributing to the integrity and mechanical resilience of hair and skin. KRT39 is not considered a receptor, enzyme, or classical therapeutic target, and there is currently no evidence it plays a significant role in common human diseases or is targeted by any drugs.

Other names: KRT39CK-39K39KA35keratin 39cytokeratin-39type I hair keratin Ka35Keratin-39

Biological functions

Structural support in hair folliclesContributes to the formation of hair and skin structure

Disease associations

Other (no direct or prominent role in major human diseases established)

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