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Keratin 89, pseudogene (KRT89P; alias psihHbB) is a nonfunctional member of the human keratin gene family, classified as a type II keratin pseudogene according to current nomenclature[2][4]. The gene is present within the keratin locus (chromosome 12q13.13) among a number of other keratin pseudogenes, but unlike functional keratin genes, it does not encode a protein and lacks a biological role in cell structure or disease[2][1][5]. Pseudogenes such as KRT89P arise through gene duplication and mutation, resulting in nonfunctional DNA segments. KRT89P is not relevant for therapy, biomarker development, or drug targeting, and entries listing it as a receptor or molecule of pharmacological interest are incorrect.
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