Keratin associated protein 8-2, pseudogene (KRTAP8-2P)

Keratin associated protein 8-2, pseudogene (KRTAP8-2P) belongs to the multigene family of keratin-associated proteins, which in mammals contribute to hair shaft structure through cross-linking and matrix formation with keratins[3]. In humans, this member is classified as a pseudogene due to the presence of gene-disrupting mutations (such as frameshifts or premature stop codons) and does not produce a functional protein product[3][1]. Although the keratin-associated protein family is critical for hair and wool formation, pseudogenes like KRTAP8-2P are considered molecular fossils with no direct biological function or disease relevance in humans[1][3]. It is not a therapeutic target and has no direct involvement as a biomarker, disease modifier, or safety concern in clinical applications. Common synonyms include KAP8A and KRTAP8P1[1][2][5].

Other names

KAP8AKRTAP8P1