Keratin associated protein 8-3, pseudogene (KRTAP8-3P)

Keratin associated protein 8-3, pseudogene (KRTAP8-3P; also known as KAP8B), is a member of the keratin-associated protein (KRTAP) gene family, which contributes to the structure and function of hair and related tissues[1][6][7][8]. However, KRTAP8-3P is classified as a pseudogene, meaning it does not encode a functional protein product and has no established biological function or disease association[1][6][7]. Pseudogenes like KRTAP8-3P can arise from gene duplication or retrotransposition events and typically accumulate disabling mutations over time, rendering them non-protein-coding[6][8]. Key points: - KRTAP8-3P is not a protein-coding gene, is not considered a therapeutic target such as a receptor, enzyme, transporter, or signal transduction molecule, and has no recognized role in human disease or therapy[1][6][8]. - There is no evidence it is targeted by any drug or used as a biomarker. - The presence of "pseudogene" in its name and functional annotation indicates its nonfunctional status and supports the "is_incorrect: true" flag for therapeutic targeting. If there is a specific focus on the functional keratin-associated protein 8-3 (not the pseudogene form), a different gene or entry would need to be considered.

Other names

KAP8Bkeratin-associated protein 8-3 pseudogeneKRTAP8-3 pseudogene