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Target intelligence / Profile preview
Lectin, mannose-binding 1-like (LMAN1L)
- Target
- LMAN1L
- Molecular classification
- Other, Lectin family, Membrane-associated carbohydrate-binding protein
01
Overview
Lectin, mannose-binding 1-like (LMAN1L) is a mannose-binding type 1 transmembrane protein containing an N-terminal lectin-like carbohydrate recognition domain, structurally similar to plant lectins. It is thought to function in transporting newly synthesized glycoproteins from the endoplasmic reticulum to the ER-Golgi intermediate compartment, participating in vesicle-mediated transport within the secretory pathway. [1][2][5][4]
- Other names
- Protein ERGIC-53-likeERGLUNQ2784/PRO7174LMAN1-like proteinERGIC-53LERGIC53-like proteinLectin mannose-binding 1-likeCOMPLEXIN 3FLJ13993slamp
02
Biological functions
Carbohydrate bindingEndoplasmic reticulum to Golgi vesicle-mediated transport
03
Disease associations
Prostate cancerChromosome 15q24 deletion syndrome
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