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A lesion is a general term describing any area of tissue abnormality, injury, or disease-induced change in organs or body structures. Lesions are classified by their morphology (e.g., macule, papule, ulcer, tumor), the tissue or organ affected (skin, brain, heart), or the underlying pathologic process (benign, malignant, infectious, inflammatory). They are a major focus of pathological diagnosis and disease staging, not a specific molecular target. Lesions can result from cancer, infection, immune reactions, trauma, or degenerative processes. The term "lesion tissue" is non-specific and does not refer to a unique molecule, protein, receptor, or therapeutic target.
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