Long intergenic non-protein coding RNA 271 (AHI1 divergent transcript) (AHI1-DT)

The AHI1 divergent transcript (AHI1-DT, also known as LINC00271) is a long noncoding RNA transcribed from the genome but not translated into protein[3]. LncRNAs are typically over 200 nucleotides, often contain multiple exons, are spliced, and may have 5′ caps and 3′ poly-A tails. They can regulate gene expression through interactions with DNA, miRNA, mRNA, and proteins, exerting effects such as modifying chromatin structure, epigenetic regulation, acting as molecular sponges for miRNA, and participating in transcriptional and post-transcriptional control[1]. However, AHI1-DT itself has not been specifically characterized in terms of disease or drug interaction in the available sources, and thus cannot be considered a conventional therapeutic target.

Other names

Long intergenic non-protein coding RNA 271AHI1 divergent transcriptLINC00271C6orf217NCRNA00271