Mannose-binding lectin family member 3, pseudogene (MBL3P)

Mannose-binding lectin family member 3, pseudogene (MBL3P) is a human gene classified as a pseudogene, meaning it shares sequence similarity with functional collectin genes but does not encode a functional protein. Functional mannose-binding lectins, such as those produced from the gene *MBL2*, are involved in the innate immune system by binding to carbohydrates on the surface of pathogens and triggering the complement system for immune defense[2][5][6]. MBL3P, however, lacks the necessary coding potential and regulatory sequences to produce a functional protein, and therefore has no proven physiological or therapeutic relevance. The actual clinically relevant members in this family are *MBL2* (for soluble MBL) and related collectins. Key clarifications: - MBL3P is not a functional protein nor a therapeutic target, but a non-coding pseudogene. - The abbreviation COLEC2 is commonly used for collectin sub-family member 2 (not a pseudogene), and the true functional MBL gene in humans is referred to as *MBL2* (not MBL3P). - No molecular, pharmacological, or disease implications are directly associated with MBL3P. Based on available evidence and authoritative sources, there is significant mislabeling or misunderstanding around MBL3P as a target, so this entry should be flagged as “is_incorrect: true” with a recommendation to use the correct gene or protein information, typically *MBL2*, if a functional mannose-binding lectin is desired[2][5][6].

Other names

MBL3PCOLEC2Mannose-binding lectin pseudogene 3Collectin sub-family member 2