Target intelligence / Profile preview

MAS related GPR family member X11, pseudogene (MRGPRX11P)

Target
MRGPRX11P
Molecular classification
Pseudogene, G protein-coupled receptor (GPCR) family (non-functional member)
01

Overview

MAS related GPR family member X11, pseudogene (MRGPRX11P) is classified as a pseudogene and does not encode a functional protein product. It belongs to the Mas-related G protein–coupled receptor (MRGPR) family, a set of class A GPCRs variably expressed in neurons and immune cells, mediating noxious sensation such as pain and itch; functional family members include MRGPRX1, X2, X3, and X4[1][2][3]. Pseudogenes in the MRGPR family represent gene sequences lacking intact open reading frames and are generally considered non-functional remnants that do not serve as therapeutic targets or drug receptors[1][3]. Therefore, MRGPRX11P is neither a receptor nor a target for drugs, and lacks known biological or disease-related functions, biomarkers, or therapeutic relevance.

Other names
MAS related GPR family member X1 pseudogeneMAS related GPR, member X1 pseudogeneMRGPRX11P

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