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Methyltransferase like 21E, pseudogene (METTL21EP) is a predicted human pseudogene with sequence similarity to the protein-lysine N-methyltransferases of the METTL family. Although METTL21EP is annotated as enabling protein methyltransferase activity and participating in methylation, there is no experimental evidence confirming its protein product or biological function. METTL21EP shares evolutionary features with methyltransferase-like proteins but has not been validated as a functional enzyme in humans. The gene is found on chromosome 13. Aliases include METTL21CP1 and methyltransferase like 21C pseudogene 1. No drugs, disease roles, or biomarker associations are recorded for METTL21EP. This entry is considered "incorrect" in the context of therapeutic targeting because it is a pseudogene, has unproven function, and is not recognized as a therapeutically actionable protein.
None (not a validated target; predicted methyltransferase activity not experimentally verified)
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