Target intelligence / Profile preview

MHC class I polypeptide-related sequence G (pseudogene) (MICG)

Target
MICG
Molecular classification
Other, Pseudogene, Related to MHC class I family (by sequence homology, not function)
01

Overview

MHC class I polypeptide-related sequence G (MICG) is a human pseudogene located on chromosome 6, annotated under several databases (e.g., Ensembl, HGNC). Unlike functional MHC class I-related proteins such as MICA and MICB, which act as stress ligands for immune activation, the MICG gene does not encode a functional protein and has no known expression, function, or disease relevance[2][3][5][6]. As such, MICG is not considered or used as a therapeutic target.

Other names
MICGMHC class I chain-related gene G pseudogeneOther nomenclature variants referencing its status as a pseudogene

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