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MHC class I polypeptide-related sequence G (MICG) is a human pseudogene located on chromosome 6, annotated under several databases (e.g., Ensembl, HGNC). Unlike functional MHC class I-related proteins such as MICA and MICB, which act as stress ligands for immune activation, the MICG gene does not encode a functional protein and has no known expression, function, or disease relevance[2][3][5][6]. As such, MICG is not considered or used as a therapeutic target.
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