Microbial Cell Components via Oxidative Damage (Active Chlorine Release)

Microbial cell components represent the ensemble of molecules and structures within microbial cells that are susceptible to damage by oxidative stress induced by active chlorine species, primarily hypochlorous acid (HOCl). This non-selective mechanism targets essential biomolecules such as proteins, lipids, nucleic acids, and carbohydrates, leading to disruption of cellular functions and ultimately cell death. Active chlorine is used in disinfection and as a key component of the innate immune response.

Other names

Oxidative damage of microbial cells by active chlorineHOCl-mediated microbial inactivationActive chlorine antimicrobial mechanism

Oxidation and chlorination of microbial cell components (proteins, lipids, nucleic acids) leading to loss of function and cell death.