MIR181A2 host gene (non-protein coding) (MIR181A2HG)

MIR181A2 host gene (MIR181A2HG) is a long non-coding RNA gene that serves primarily as the host transcript for the microRNA miR-181a-2[3]. The gene itself does not code for a protein, but its expression gives rise to miR-181a-2, which participates in the regulation of gene expression post-transcriptionally by targeting other RNAs through the RNA-induced silencing complex (RISC)[2][3]. While the host gene's biological role is largely defined by its function in miRNA production, its overexpression or alteration may have regulatory effects on cellular signaling and is associated with various disease contexts through its product miR-181a-2[1][2][7]. There is currently no known drug acting directly on MIR181A2HG, and its primary relevance as a target comes from the functional consequences of the miRNAs it hosts rather than the lncRNA itself[2][3][7].

Other names

MIR181A2HGMIR181A2 host geneMIR181A2 host gene (non-protein coding)MIR181A2HG RNAENSG00000224020 (Ensembl)NCBI Gene: 100379345HGNC: 37188