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MIR3663 host gene (non-protein coding) (MIR3663HG)
- Target
- MIR3663HG
- Molecular classification
- Long non-coding RNA (lncRNA), RNA gene
01
Overview
MIR3663 host gene (MIR3663HG) is a human gene located on chromosome 10 encoding a long non-coding RNA (lncRNA)[2][3]. It serves as the host for the microRNA miR-3663. MIR3663HG itself is not known to be a therapeutic target or associated with direct disease roles. Its most studied relevance is as a host for miR-3663, which acts as a tumor suppressor in gastric cancer through modulation of cell cycle regulators such as Cyclin D1 and retinoblastoma protein, with low miR-3663-3p expression linked to recurrence risk in patients[1]. No drugs, safety concerns, or biomarker status are directly attributed to MIR3663HG.
- Other names
- MIR3663HGMIR3663 host geneMIR3663 host gene (non-protein coding)
02
Biological functions
Host for miR-3663Potential regulation of nearby or embedded genes via lncRNA mechanisms
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