Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 pseudogene 5 (MTND1P5)

MTND1P5, or "MT-ND1 pseudogene 5" (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 pseudogene 5), is not an active protein-coding gene but rather a pseudogene for the MT-ND1 subunit of mitochondrial Complex I. It does not encode a functional protein and is not considered a therapeutic target.\n\nMTND1P5 is a pseudogene located within the nuclear genome that resembles the mitochondrial gene MT-ND1, which normally encodes a core subunit of NADH:ubiquinone oxidoreductase (Complex I) of the mitochondrial respiratory chain. Unlike functional MT-ND1, MTND1P5 does not encode an active enzyme or protein, and has no described biological function, disease association, or therapeutic relevance. Pseudogenes generally arise from gene duplication or retrotransposition events and are considered “dead” genes lacking protein coding ability or regulatory function. Information and disease relevance apply only to MT-ND1, not to MTND1P5[3][4][6].\n\nKey Points:\n- Not a molecular target: MTND1P5 is a pseudogene and does not act as a receptor, enzyme, transporter, or therapeutic target.\n- Incorrect for drug target queries: If searched as a drug target, this is incorrect; information on disease and therapeutics concerns only the active MT-ND1 gene[3][6].\n- No clinical or biological data: MTND1P5 has not been implicated in disease, drug interactions, or biomarker applications[6].\n\nIf you require structured information on the true target, search for MT-ND1 (Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1)[2][3][6], not its pseudogene.

Other names

MT-ND1 pseudogene 5MTND1P5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 pseudogene 5