Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 pseudogene 25 (MTND6P25)

MTND6P25, or "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 pseudogene 25," is a **pseudogene** related to the MT-ND6 gene, which provides instructions for producing a subunit (ND6) of the mitochondrial respiratory chain complex I[1][2]. However, as a pseudogene, MTND6P25 does not encode a functional protein and is **not considered a therapeutic target, receptor, enzyme, or transporter**. Information about this pseudogene's structure, biological function, or role in disease is not available in the scientific literature. The functional MT-ND6 gene is crucial for mitochondrial electron transport and ATP synthesis, with pathogenic mutations implicated in mitochondrial diseases such as Leber hereditary optic neuropathy and Leigh disease[1][2][3][4]. In contrast, pseudogenes like MTND6P25 typically do not contribute to biological pathways or serve as drug targets. **Key points supporting classification as "incorrect/irrelevant target":** - "Pseudogene" indicates it does not code for a functional protein. - No evidence for use as a therapeutic target, biomarker, or drug interaction[2][3]. - All known functional data relate to the protein-coding MT-ND6, *not* its pseudogenes[1][2][3]. In summary, **MTND6P25** is a non-coding pseudogene, not a relevant drug or research target, and should not be confused with the functional mitochondrial MT-ND6 gene.

Other names

MT-ND6 pseudogene 25MTND6P25mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 pseudogene 25