MKI67 (FHA domain) interacting nucleolar phosphoprotein pseudogene 8 (NIFKP8)

NIFK pseudogene 8 (NIFKP8), also referenced as MKI67IPP8, is a pseudogene in humans that shares homology with the MKI67IP (MKI67 FHA domain-interacting nucleolar phosphoprotein) gene, but does not encode a functional protein itself[2][3][4][7]. Pseudogenes are gene sequences that resemble known genes but are not translated into functional proteins due to mutations or other genomic alterations[3][7]. NIFKP8 lacks evidence of expression or protein function, and its biological significance remains undefined in the current literature. Unlike some pseudogenes that may have noncoding RNA functions, there is no published evidence that NIFKP8 is a functional lncRNA or is implicated in disease. The gene is cataloged primarily in gene databases and is not recognized as a therapeutic or diagnostic target[3][7][4]. Summary: NIFKP8 is a pseudogene, not a functional gene or known drug target. It should not be confused with similar functional genes (such as MKI67IP) or other pseudogenes/lncRNAs reported as oncogenic (such as DUXAP8)[1]. There are no known biological, pathological, or therapeutic associations with NIFKP8[3][7].

Other names

NIFK pseudogene 8MKI67IPP8nucleolar protein interacting with the FHA domain of MKI67 pseudogene 8