MTOR antisense RNA 1 (non-protein coding) (MTOR-AS1)

MTOR antisense RNA 1 (MTOR-AS1) is a long non-coding RNA (lncRNA) gene transcribed antisense to the MTOR locus[3]. It does not encode a protein and is classified as a non-protein coding RNA. Diseases associated with MTOR-AS1 include Smith-Kingsmore syndrome, but there is no evidence in the current literature to support its role as a direct therapeutic or druggable target. There are no known small molecule drugs or approved therapeutics that selectively act on MTOR-AS1. Its functional characterization and molecular mechanisms remain poorly defined, with no data reported as a validated biomarker, safety concern, or primary mediator of disease outside rare genetic associations[3].\n\nNote:\n- Most information available is minimal and indicates only its association with a disease rather than a direct mechanistic or therapeutic targeting role[3].\n- Ensure distinction from the mTOR protein or mTORC1/2 complexes, which are well-characterized kinase targets in oncology and metabolism—MTOR-AS1 is a non-coding RNA and not a protein kinase or receptor[1][3].

Other names

MTOR-AS1MTOR antisense RNA 1 (non-protein coding)MTORAS1