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Mucin 17, Cell Surface Associated

Molecular classification: Mucin, Glycoprotein, Transmembrane protein

Overview

Mucin-17 is a membrane-bound mucin protein primarily expressed on the apical surface of epithelial cells in the small and large intestines. As a transmembrane mucin, it plays key roles in protecting gut epithelial cells from physical and microbial insults and contributes to maintaining intestinal barrier function. Its antiadhesive properties may also contribute to tumor immune evasion or progression.

Other names: MUC3MUC-17mucin 17cell surface associated

Biological functions

CytoprotectionBarrier functionSignal transductionAnti-adhesion

Disease associations

Inflammatory conditions of the gutTumorigenesisColon adenocarcinoma

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