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Muscles of the pelvic floor (including puborectalis, pubococcygeus, iliococcygeus, coccygeus)

Molecular classification
Other (group of skeletal muscles)
01

Overview

The **pelvic muscles**, or muscles of the pelvic floor, form a basin-shaped diaphragm that consists primarily of the skeletal muscles levator ani (puborectalis, pubococcygeus, iliococcygeus) and coccygeus[1][2][3][4]. They provide critical support for pelvic viscera, contribute to urinary and fecal continence, aid in sexual function and childbirth, and prevent pelvic organ prolapse. These muscles are innervated by the pudendal and sacral nerves and receive blood from branches of the internal iliac artery[2][3]. Clinical relevance includes their role in continence, support, and common conditions such as pelvic floor dysfunction and organ prolapse.

Other names
pelvic floor musclespelvic diaphragmlevator ani musclespelvic diaphragm muscles
02

Mechanism of action

N/A for "pelvic muscle"; drug mechanisms may include neuromuscular blockade, but this is not a direct molecular interaction with a specific receptor/enzyme.

03

Biological functions

Physical support of pelvic visceraConstrictor mechanisms for anal canal, vagina, urethraMaintenance of continence (urinary and fecal)Prevention of pelvic organ prolapseAssistance in childbirth
04

Disease associations

Pelvic floor dysfunctionPelvic organ prolapseUrinary incontinenceFecal incontinence
05

Safety considerations

Injury during childbirthSurgical traumaOveractive or underactive pelvic muscles may contribute to dysfunction
06

Interacting drugs

None directly; however, muscle function may be influenced by drugs affecting neuromuscular transmission, such as muscle relaxants, or by botulinum toxin (off-label) for some types of pelvic floor dysfunction. No drugs directly target "pelvic muscle" as a molecular entity.
07

Biomarkers

N/A for "pelvic muscle" as a group; imaging modalities (US, MRI), manometry are tools for functional assessment.

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