Peroxidase (POD)

Peroxidases are a large and diverse group of enzymes that catalyze the oxidation of various substrates using hydrogen peroxide or other peroxides as electron acceptors. They are crucial for peroxide detoxification, biosynthesis, immune responses, and environmental remediation. These enzymes play a vital role in protecting cells from oxidative damage and participate in diverse biological processes. Peroxidases are classified based on their cofactors (heme or non-heme) and have found significant applications in biotechnology, diagnostics, and chemical synthesis.

Other names

Peroxide reductaseHRP (Horseradish Peroxidase)Myeloperoxidase (MPO)Lactoperoxidase (LPO)Thyroid peroxidase (TPO)Glutathione peroxidaseAlkyl hydroperoxide reductaseVanadium bromoperoxidaseManganese-dependent peroxidase

Catalyzes the reduction of hydrogen peroxide or organic hydroperoxides with the simultaneous oxidation of an electron donor substrate. The enzyme cycles through different oxidation states during the reaction.