Myosin, light chain 12-like, regulatory pseudogene

The "myosin, light chain 12-like, regulatory pseudogene" is a non-protein-coding pseudogene related to the myosin light chain family. Unlike canonical myosin light chain proteins (such as MYL12A or MYL12B), this pseudogene does not produce a functional regulatory light chain subunit and does not directly participate in myosin-mediated contractile mechanics. Some myosin light chain-related pseudogenes can act in gene regulation by affecting the RNA stability or transcription of their parental genes, potentially impacting cellular processes such as proliferation. However, no evidence supports a direct therapeutic or biomarker role for this specific pseudogene (ENSG00000263199). Pseudogenes may sometimes be misclassified as protein-coding targets in large genomic datasets; careful curation is required to avoid such errors when selecting drug targets[2][4]. In summary, ENSG00000263199 represents a regulatory pseudogene, not a canonical therapeutic target[2][4]. If your intent is to study a druggable myosin light chain protein, targets such as MYL12A or MYL12B (protein-coding genes) should be used instead[6].

Other names

MYL12-like pseudogeneMYL12 pseudogenemyosin regulatory light chain 12-like pseudogene