Target intelligence / Profile preview

NADH:ubiquinone oxidoreductase subunit B11 pseudogene 1 (NDUFB11P1)

Target
NDUFB11P1
Molecular classification
Other (Pseudogene)
01

Overview

NDUFB11P1 is a human pseudogene related to the protein-coding gene NDUFB11, which is a subunit of mitochondrial NADH:ubiquinone oxidoreductase (Complex I)[1][3][5]. Pseudogenes are non-functional copies of genes; they may not be transcribed or translated, and typically do not produce functional protein products. Although some pseudogenes have been shown to exert regulatory effects on gene expression or participate in disease-related processes, NDUFB11P1 itself is not known to encode a functional protein, serve as a receptor, or act as a direct therapeutic target. Currently, there is no evidence that NDUFB11P1 is involved in human disease or interacts with drugs, nor is it considered a biomarker or safety concern[1][6]. Summary of Key Issue: NDUFB11P1 is mistakenly listed as a drug target or functional biomolecule; it is a pseudogene with no established protein product, therapeutic targeting, or direct biological activity. If the intention was to capture information on mitochondrial Complex I subunits, the correct entry would be "NADH:ubiquinone oxidoreductase subunit B11 (NDUFB11)" rather than the pseudogene NDUFB11P1[3][7].

Other names
NDUFB11P1NDUFB11PNADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa pseudogeneNADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, pseudogene 1
02

Biological functions

Pseudogenes may have regulatory roles, such as acting as competitive endogenous RNAs (ceRNAs) or influencing gene expression, but there is no direct evidence for NDUFB11P1 specifically.
03

Disease associations

Pseudogenes in general have been shown to play regulatory roles in cancer and other diseases, but NDUFB11P1 specifically is not established as playing a direct disease role.

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