NADH:ubiquinone oxidoreductase subunit B3 pseudogene 5 (NDUFB3P5)

NDUFB3P5 is a human pseudogene that lacks the capability to encode a functional NADH:ubiquinone oxidoreductase subunit B3 protein and typically contains mutations or sequence defects that preclude the synthesis of the active protein[1][4][5]. It is labeled as a processed or non-functional copy of the NDUFB3 gene, which in its functional form is a subunit of mitochondrial respiratory chain complex I. Pseudogenes are generally transcriptionally silent but may rarely be transcribed; their RNA may have regulatory effects on gene expression by serving as decoys for microRNAs or affecting stability of related mRNAs in very specific contexts (no evidence for this pseudogene)[5]. NDUFB3P5 is not a receptor, enzyme, transporter, or transcription factor; it is not relevant as a drug target or biomarker and has no reported disease involvement[1][4][5].

Other names

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa pseudogene 5