NADH:ubiquinone oxidoreductase subunit B4 pseudogene 2 (NDUFB4P2)

NDUFB4P2, or NADH:ubiquinone oxidoreductase subunit B4 pseudogene 2, is classified as a **pseudogene** in the human genome and does not encode a functional protein[1]. It is related in sequence to the protein-coding gene NDUFB4, which is an accessory subunit of Complex I (NADH:ubiquinone oxidoreductase) in the mitochondrial respiratory chain[3][4][7]. However, as a pseudogene, NDUFB4P2 is not involved in the assembly or function of this enzyme complex, nor is it known to be associated with any biological activity, physiological or disease role, or to be a therapeutic target[1]. No drugs or biomarkers are linked to this pseudogene, and it is not considered relevant in clinical or pharmacological contexts. **Context and supporting details:** - The NDUFB4 gene encodes a genuine mitochondrial protein subunit; by contrast, NDUFB4P2 is a non-coding pseudogene[1]. - Pseudogenes typically do not produce functional proteins and are generally not considered druggable targets or involved in recognized biological pathways. - There is no evidence that NDUFB4P2 has a role in disease or can be used in patient selection, safety monitoring, or as a biomarker. - The only established information is its genomic, non-functional status, and not the properties used to describe drugs or receptors.

Other names

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa pseudogene 2NDUFB4P2